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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
1999 4
2000 5
2001 2
2002 2
2003 2
2004 5
2005 4
2006 3
2007 1
2008 2
2009 2
2010 4
2011 8
2012 6
2013 6
2014 10
2015 13
2016 10
2017 5
2018 13
2019 11
2020 16
2021 22
2022 12
2023 14
2024 5

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166 results

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Page 1
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
Cardoso AL, Fernandes A, Aguilar-Pimentel JA, de Angelis MH, Guedes JR, Brito MA, Ortolano S, Pani G, Athanasopoulou S, Gonos ES, Schosserer M, Grillari J, Peterson P, Tuna BG, Dogan S, Meyer A, van Os R, Trendelenburg AU. Cardoso AL, et al. Ageing Res Rev. 2018 Nov;47:214-277. doi: 10.1016/j.arr.2018.07.004. Epub 2018 Jul 30. Ageing Res Rev. 2018. PMID: 30071357 Free article. Review.
Based on our search we would propose a core panel of frailty biomarkers consisting of (1) CXCL10 (C-X-C motif chemokine ligand 10), IL-6 (interleukin 6), CX3CL1 (C-X3-C motif chemokine ligand 1), (2) GDF15 (growth differentiation factor 15), FNDC5 (fibronectin type III domain con …
Based on our search we would propose a core panel of frailty biomarkers consisting of (1) CXCL10 (C-X-C motif chemokine ligand 10), IL-6 (in …
PRMT1 driven PTX3 regulates ferritinophagy in glioma.
Lathoria K, Gowda P, Umdor SB, Patrick S, Suri V, Sen E. Lathoria K, et al. Autophagy. 2023 Jul;19(7):1997-2014. doi: 10.1080/15548627.2023.2165757. Epub 2023 Jan 16. Autophagy. 2023. PMID: 36647288 Free PMC article.
Transcriptional activation and subsequent secretion of PTX3 from cells was required for maintaining macroautophagic/autophagic balance as pharmacological or genetic ablation of PTX3 secretion in wild-type IDH1 significantly increased autophagic flux. Additionally, …
Transcriptional activation and subsequent secretion of PTX3 from cells was required for maintaining macroautophagic/autophagic balanc …
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3.
Fornai F, Carrizzo A, Ferrucci M, Damato A, Biagioni F, Gaglione A, Puca AA, Vecchione C. Fornai F, et al. Int J Biochem Cell Biol. 2015 Dec;69:70-4. doi: 10.1016/j.biocel.2015.10.017. Epub 2015 Oct 17. Int J Biochem Cell Biol. 2015. PMID: 26485684 Review.
In the present review we discuss the good and bad cops of PTX3 concerning multifacted effects on inflammation, innate immunity, brain diseases and tumorigenesis. Finally, a perspective on PTX3 and autophagy is provided as a convergent pathway....
In the present review we discuss the good and bad cops of PTX3 concerning multifacted effects on inflammation, innate immunity, br …
The Long Pentraxin PTX3 in Bone Homeostasis and Pathology.
Parente R, Sobacchi C, Bottazzi B, Mantovani A, Grčevic D, Inforzato A. Parente R, et al. Front Immunol. 2019 Nov 8;10:2628. doi: 10.3389/fimmu.2019.02628. eCollection 2019. Front Immunol. 2019. PMID: 31787987 Free PMC article. Review.
Despite the impressive diversity in structure, source, and regulation across PRMs, these all share remarkably similar functions inasmuch as they recognize microbes and damaged tissues, activate complement, exert opsono-phagocytic activities, and regulate inflammation. The long pe …
Despite the impressive diversity in structure, source, and regulation across PRMs, these all share remarkably similar functions inasmuch as …
The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury.
Rodriguez-Grande B, Swana M, Nguyen L, Englezou P, Maysami S, Allan SM, Rothwell NJ, Garlanda C, Denes A, Pinteaux E. Rodriguez-Grande B, et al. J Cereb Blood Flow Metab. 2014 Mar;34(3):480-8. doi: 10.1038/jcbfm.2013.224. Epub 2013 Dec 18. J Cereb Blood Flow Metab. 2014. PMID: 24346689 Free PMC article.
Here we show that PTX3 is expressed in neurons and glia in response to cerebral ischemia, and that the proinflammatory cytokine interleukin-1 (IL-1) is a key driver of PTX3 expression in the brain after experimental stroke. Gene deletion of PTX3 had no …
Here we show that PTX3 is expressed in neurons and glia in response to cerebral ischemia, and that the proinflammatory cytokine inter …
CGRP and PTX3 as Predictors of Efficacy of Onabotulinumtoxin Type A in Chronic Migraine: An Observational Study.
Domínguez C, Vieites-Prado A, Pérez-Mato M, Sobrino T, Rodríguez-Osorio X, López A, Campos F, Martínez F, Castillo J, Leira R. Domínguez C, et al. Headache. 2018 Jan;58(1):78-87. doi: 10.1111/head.13211. Epub 2017 Nov 13. Headache. 2018. PMID: 29131327
METHODS: We measured serum levels of biomarkers of inflammation (IL-6, IL-10, TNF-alpha, and hs-CRP), endothelial dysfunction (PTX3 and sTWEAK), blood-brain barrier disruption (cFN), brain damage (S100b, NSE), and trigemino-vascular activation (CGRP) by ELISA …
METHODS: We measured serum levels of biomarkers of inflammation (IL-6, IL-10, TNF-alpha, and hs-CRP), endothelial dysfunction (PTX3 a …
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology.
Oggioni M, Mercurio D, Minuta D, Fumagalli S, Popiolek-Barczyk K, Sironi M, Ciechanowska A, Ippati S, De Blasio D, Perego C, Mika J, Garlanda C, De Simoni MG. Oggioni M, et al. Sci Rep. 2021 May 5;11(1):9616. doi: 10.1038/s41598-021-89032-7. Sci Rep. 2021. PMID: 33953334 Free PMC article.
We measured PTX3 mRNA and protein in the brain and its circulating levels at different time point post-injury, and assessed behavioral deficits and brain damage progression in PTX3 KO mice. ...In the brain, PTX3 mRNA was upregulated in di …
We measured PTX3 mRNA and protein in the brain and its circulating levels at different time point post-injury, and assessed be …
Diagnostic values of serum BNP, PTX3, and VEGF in acute pulmonary embolism complicated by pulmonary artery hypertension and their correlations with severity of pulmonary artery hypertension.
Zheng Q, Zhang B, Lu N, Li X, Jin B, Jin P. Zheng Q, et al. Immun Inflamm Dis. 2023 Sep;11(9):e986. doi: 10.1002/iid3.986. Immun Inflamm Dis. 2023. PMID: 37773724 Free PMC article.
OBJECTIVE: This paper aimed to unveil the diagnostic values of serum brain natriuretic peptide (BNP), pentraxin 3 (PTX3), and vascular endothelial growth factor (VEGF) in acute pulmonary embolism complicated by pulmonary artery hypertension (APE-PAH) and their corre …
OBJECTIVE: This paper aimed to unveil the diagnostic values of serum brain natriuretic peptide (BNP), pentraxin 3 (PTX3), and …
Mena regulates nesprin-2 to control actin-nuclear lamina associations, trans-nuclear membrane signalling and gene expression.
Li Mow Chee F, Beernaert B, Griffith BGC, Loftus AEP, Kumar Y, Wills JC, Lee M, Valli J, Wheeler AP, Armstrong JD, Parsons M, Leigh IM, Proby CM, von Kriegsheim A, Bickmore WA, Frame MC, Byron A. Li Mow Chee F, et al. Nat Commun. 2023 Mar 23;14(1):1602. doi: 10.1038/s41467-023-37021-x. Nat Commun. 2023. PMID: 36959177 Free PMC article.
CRISPR-mediated Mena depletion causes altered nuclear morphology, reduces tyrosine phosphorylation of the nuclear membrane protein emerin and downregulates expression of the immunomodulatory gene PTX3 via the recruitment of its enhancer to the nuclear periphery. ...
CRISPR-mediated Mena depletion causes altered nuclear morphology, reduces tyrosine phosphorylation of the nuclear membrane protein emerin an …
Long Covid: where we stand and challenges ahead.
Mantovani A, Morrone MC, Patrono C, Santoro MG, Schiaffino S, Remuzzi G, Bussolati G; Covid-19 Commission of the Accademia Nazionale dei Lincei. Mantovani A, et al. Cell Death Differ. 2022 Oct;29(10):1891-1900. doi: 10.1038/s41418-022-01052-6. Epub 2022 Sep 7. Cell Death Differ. 2022. PMID: 36071155 Free PMC article. Review.
PASC affects a wide range of diverse organs and systems, with manifestations involving lungs, brain, the cardiovascular system and other organs such as kidney and the neuromuscular system. ...
PASC affects a wide range of diverse organs and systems, with manifestations involving lungs, brain, the cardiovascular system and ot …
166 results